Singapore Clinical Trial: IZABRIGHT-Lung01: A Randomized, Open-label, Phase 2/3 Study of Izalontamab Brengitecan (BMS-986507) versus Platinum-based Chemotherapy in Patients with EGFR-mutated Non-small Cell Lung Cancer and Disease Progression on EGFR Tyrosine Kinase Inhibitor Therapy.

Singapore, Aug. 8 -- The Health Sciences Authority received information related to the study titled 'IZABRIGHT-Lung01: A Randomized, Open-label, Phase 2/3 Study of Izalontamab Brengitecan (BMS-986507)... Read More

Clinical Trial: Unilateral and Bilateral Resistance Training in Hypertension

U.S., Aug. 8 -- ClinicalTrials.gov registry received information related to the study (NCT07751445) titled 'Unilateral and Bilateral Resistance Training in Hypertension' on Aug. 02. Brief Summary: Hy... Read More

Clinical Trial: Daily Tadalafil as Adjunctive Therapy Versus Monotherapy for PDE5 Inhibitor-Resistant Erectile Dysfunction

U.S., Aug. 8 -- ClinicalTrials.gov registry received information related to the study (NCT07753720) titled 'Daily Tadalafil as Adjunctive Therapy Versus Monotherapy for PDE5 Inhibitor-Resistant Erecti... Read More

Clinical Trial: Effects of Structural Integration on Chest Wall Expansion Among COPD Patients

U.S., Aug. 8 -- ClinicalTrials.gov registry received information related to the study (NCT07752420) titled 'Effects of Structural Integration on Chest Wall Expansion Among COPD Patients' on Aug. 04. ... Read More

Singapore Clinical Trial: ROSETTA CRC-203: A Blinded, Randomized Phase 2/3 Study of Pumitamig in Combination with Chemotherapy Versus Bevacizumab in Combination with Chemotherapy in Participants with Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

Singapore, Aug. 8 -- The Health Sciences Authority received information related to the study titled 'ROSETTA CRC-203: A Blinded, Randomized Phase 2/3 Study of Pumitamig in Combination with Chemotherap... Read More

Clinical Trial: Non-Interventional Study on the Prevalence of Cardiac Amyloidosis in Patients With Higher-Grade Aortic Valve Stenosis - Evaluation Using Echocardiography, Computed Tomography, Tc99-SPECT/CT and Cardiac Magnetic Resonance Imaging (CMR)

U.S., Aug. 8 -- ClinicalTrials.gov registry received information related to the study (NCT07752732) titled 'Non-Interventional Study on the Prevalence of Cardiac Amyloidosis in Patients With Higher-Gr... Read More

Singapore Clinical Trial: A Phase 3, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Safety and Efficacy of L606 (Treprostinil Liposome Inhalation Suspension) in Participants with Pulmonary Hypertension Associated with Interstitial Lung Disease (WHO Group 3)

Singapore, Aug. 8 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Safety... Read More

Singapore Clinical Trial: A Phase III, Randomized, Open-Label, Multicenter, Global Study of Puxitatug Samrotecan (AZD8205) Monotherapy versus Physician’s Choice of Chemotherapy in Participants with B7-H4-Selected Advanced/Metastatic Endometrial Cancer Who Progressed On or After Platinum-Based Chemotherapy and Anti-PD-1/Anti-PD-L1 Therapy (BLUESTAR-Endometrial01)

Singapore, Aug. 8 -- The Health Sciences Authority received information related to the study titled 'A Phase III, Randomized, Open-Label, Multicenter, Global Study of Puxitatug Samrotecan (AZD8205) Mo... Read More

Clinical Trial: Evaluation of the Effects of Colipral on Microbiota Gut Composition in Patients Presenting With Ulcerative Colitis During Remission Phase and Functional Disorders

U.S., Aug. 8 -- ClinicalTrials.gov registry received information related to the study (NCT07751081) titled 'Evaluation of the Effects of Colipral on Microbiota Gut Composition in Patients Presenting W... Read More

Clinical Trial: Prospective Multicenter Study Evaluating Myval TAVR Safety and Effectiveness in High-risk Severe AR

U.S., Aug. 8 -- ClinicalTrials.gov registry received information related to the study (NCT07751965) titled 'Prospective Multicenter Study Evaluating Myval TAVR Safety and Effectiveness in High-risk Se... Read More

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